Direct flights from Knoxville to Chicago

Did you mean Flights from Chicago to Knoxville?

Knoxville

United States

TYS

McGhee Tyson Airport

Chicago

United States

ORD

Chicago O'Hare International Airport

Route: Nonstop service available
Distance: 475 miles
Marketing airlines: 15 airlines
Aircraft: 9 aircraft types
Dates: Oct 19, 2026 – Oct 17, 2027

Observed award fares

A sample of one-way prices for one traveler from Roame’s fare cache. Points, fees, and seats describe the same observation. Availability can change; confirm with the loyalty program before transferring points.

Lowest price in this limited sample: 4,500 points + $25.00 for TYS → ORD, Economy, on 2026-10-30, booked with Alaska Atmos Rewards. This is an observed fare, not a guaranteed price or the lowest price across all dates and programs.

Departure window: 2026-10-23 – 2026-11-21.

TYS → ORDEconomy
AA4751
4,500 points+ $25.00
Departure
2026-10-30
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 19:58
TYS → ORDEconomy
AA3653
4,500 points+ $25.00
Departure
2026-11-09
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-22 01:52
TYS → ORDEconomy
AA4229
4,500 points+ $25.00
Departure
2026-11-10
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 21:13
TYS → ORDEconomy
AA5408
4,500 points+ $25.00
Departure
2026-11-10
Seats seen
4
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 21:13
TYS → ORDEconomy
AA3653
4,500 points+ $25.00
Departure
2026-11-10
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 21:13
TYS → ORDEconomy
AA4229
4,500 points+ $25.00
Departure
2026-11-11
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 20:49
TYS → ORDEconomy
AA5408
4,500 points+ $25.00
Departure
2026-11-11
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 20:49
TYS → ORDEconomy
AA3653
4,500 points+ $25.00
Departure
2026-11-12
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 15:00
TYS → ORDEconomy
AA4229
4,500 points+ $25.00
Departure
2026-11-13
Seats seen
5
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 23:06
TYS → ORDEconomy
AA3653
4,500 points+ $25.00
Departure
2026-11-13
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 23:06
TYS → ORDEconomy
AA3653
4,500 points+ $25.00
Departure
2026-11-19
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 10:42
TYS → ORDEconomy
AA4229
4,500 points+ $25.00
Departure
2026-11-19
Seats seen
9
Book with
Alaska Atmos Rewards
Observed (UTC)
2026-10-21 10:42

Knoxville to Chicago route overview

McGhee Tyson Airport (TYS) serves Knoxville; Chicago O'Hare International Airport (ORD) serves Chicago.

The airports are 475 miles apart by great-circle distance.

Roame's current schedule feed shows nonstop service from TYS to ORD.

Marketing airlines listed in the current schedule, including codeshare sellers, are American Airlines (AA), Air Canada (AC), Alaska Airlines (AS), Avianca (AV), British Airways (BA), Aer Lingus (EI), Emirates (EK), Iberia (IB), Japan Airlines (JL), Lufthansa (LH), All Nippon Airways (NH), Air New Zealand (NZ), Qatar Airways (QR), Royal Jordanian (RJ) and United Airlines (UA). This list does not identify the operating airline for each flight; check the flight details before booking.

Published schedule dates span Oct 19, 2026 – Oct 17, 2027.

Marketing airlines on the Knoxville to Chicago route

These are marketing airlines, including codeshare sellers. This list does not identify the operating airline for each flight; check the flight details before booking.

Air Canada (AC)Codeshare only
Alaska Airlines (AS)Codeshare only
Avianca (AV)Codeshare only
British Airways (BA)Codeshare only
Aer Lingus (EI)Codeshare only
Emirates (EK)Codeshare only
Iberia (IB)Codeshare only
Japan Airlines (JL)Codeshare only
Lufthansa (LH)Codeshare only
All Nippon Airways (NH)Codeshare only
Air New Zealand (NZ)Codeshare only
Qatar Airways (QR)Codeshare only
Royal Jordanian (RJ)Codeshare only

Airline alliance affiliations represented: Oneworld, Star Alliance

Aircraft flying from TYS to ORD

Frequently asked questions

Which airports serve the Knoxville to Chicago route?

McGhee Tyson Airport (TYS) is the origin airport and Chicago O'Hare International Airport (ORD) is the destination airport.

How far is Chicago from Knoxville?

TYS and ORD are approximately 475 miles apart by great-circle distance.

Are there direct flights from TYS to ORD?

Yes. Roame's current schedule feed shows nonstop service from TYS to ORD.

Which airlines market flights from TYS to ORD?

Which aircraft fly from TYS to ORD?

Aircraft listed in the current schedule include Airbus A319 (319), Airbus A320 (320), CR5, Canadair Regional Jet 700 | Regional Jet 550 (CR7), CRJ, Embraer 170 (E70), Embraer 175 (short wing) (E75), Embraer 175 (long wing) (E7W) and JET.