La Guardia Airport (LGA) is the origin airport and McGhee Tyson Airport (TYS) is the destination airport.
LGA and TYS are approximately 647 miles apart by great-circle distance.
Yes. Roame's current schedule feed shows nonstop service from LGA to TYS.
Airlines represented in the current schedule are American Airlines (AA), Delta Air Lines (DL), Porter Airlines (PD) and WestJet (WS).
Aircraft listed in the current schedule include Canadair Regional Jet 900 (CR9) and Embraer 175 (short wing) (E75).