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Direct flights from Knoxville to New Orleans

Did you mean Flights from New Orleans to Knoxville?

Flightmap/Flights from TYS/TYS to MSY

Knoxville

United States

TYS

McGhee Tyson Airport

New Orleans

United States

MSY

Louis Armstrong New Orleans International Airport

Route
Nonstop service available
Distance
542 miles
Marketing airlines
2 airlines
Aircraft
2 aircraft types
Dates
Nov 22 – 22, 2026

Observed award fares

A sample of one-way prices for one traveler from Roame’s fare cache. Points, fees, and seats describe the same observation. Availability can change; confirm with the loyalty program before transferring points.

Departure window: 2026-10-23 – 2026-11-21.

No recent fares appear in this limited preview. This does not mean the route is sold out. Use the search controls to check other dates and routes.

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Explore these airports and cities

  • Flights from TYS
  • Flights to MSY

Knoxville to New Orleans route overview

McGhee Tyson Airport (TYS) serves Knoxville; Louis Armstrong New Orleans International Airport (MSY) serves New Orleans.

The airports are 542 miles apart by great-circle distance.

Roame's current schedule feed shows nonstop service from TYS to MSY.

Marketing airlines listed in the current schedule, including codeshare sellers, are American Airlines (AA) and Southwest Airlines (WN). This list does not identify the operating airline for each flight; check the flight details before booking.

Published schedule dates span Nov 22 – 22, 2026.

Marketing airlines on the Knoxville to New Orleans route

These are marketing airlines, including codeshare sellers. This list does not identify the operating airline for each flight; check the flight details before booking.

  • American Airlines (AA)Codeshare only

Airline alliance affiliations represented: Oneworld

Aircraft flying from TYS to MSY

Frequently asked questions

Which airports serve the Knoxville to New Orleans route?

McGhee Tyson Airport (TYS) is the origin airport and Louis Armstrong New Orleans International Airport (MSY) is the destination airport.

How far is New Orleans from Knoxville?

TYS and MSY are approximately 542 miles apart by great-circle distance.

Are there direct flights from TYS to MSY?

Yes. Roame's current schedule feed shows nonstop service from TYS to MSY.

Which airlines market flights from TYS to MSY?

Marketing airlines listed in the current schedule, including codeshare sellers, are American Airlines (AA) and Southwest Airlines (WN). This list does not identify the operating airline for each flight; check the flight details before booking.

Which aircraft fly from TYS to MSY?

Aircraft listed in the current schedule include Boeing 737 MAX 8 (7M8) and Embraer 175 (short wing) (E75).

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