McGhee Tyson Airport (TYS) serves Knoxville; Valley International Airport (HRL) serves Harlingen.
The airports are 1,043 miles apart by great-circle distance.
Roame's current schedule feed lists service with stops from TYS to HRL, but no nonstop service.
Marketing airlines listed in the current schedule, including codeshare sellers, are Southwest Airlines (WN). This list does not identify the operating airline for each flight; check the flight details before booking.
Published schedule dates span Mar 11 – Apr 5, 2027.