STL and RDU are approximately 666 miles apart by great-circle distance.
Yes. Roame's current schedule feed shows nonstop service from STL to RDU.
Airlines represented in the current schedule are Southwest Airlines (WN).
Aircraft listed in the current schedule include Boeing 737-800 Winglets (73H), Boeing 737 MAX 8 (7M8), 7S7 and JET.