John Wayne Airport-Orange County Airport (SNA) serves Santa Ana; Lambert St Louis International Airport (STL) serves St Louis.
The airports are 1,566 miles apart by great-circle distance.
Roame's current schedule feed lists service with stops from SNA to STL, but no nonstop service.
Marketing airlines listed in the current schedule, including codeshare sellers, are Southwest Airlines (WN). This list does not identify the operating airline for each flight; check the flight details before booking.
Published schedule dates span Nov 29, 2026 – May 31, 2027.