Flights from Medford to Knoxville

Medford

United States

MFR

Rogue Valley International Medford Airport

Knoxville

United States

TYS

McGhee Tyson Airport

Medford to Knoxville route overview

Rogue Valley International Medford Airport (MFR) serves Medford; McGhee Tyson Airport (TYS) serves Knoxville.

The airports are 2,114 miles apart by great-circle distance.

Roame's current schedule feed lists service with stops from MFR to TYS, but no nonstop service.

Airlines represented in the current schedule are United Airlines (UA).

Published schedule dates span Dec 3 – 3, 2026.

Airline alliance affiliations represented: Star Alliance

Which airports serve the Medford to Knoxville route?

Rogue Valley International Medford Airport (MFR) is the origin airport and McGhee Tyson Airport (TYS) is the destination airport.

How far is Knoxville from Medford?

MFR and TYS are approximately 2,114 miles apart by great-circle distance.

Are there direct flights from MFR to TYS?

No. Roame's current schedule feed lists service with stops from MFR to TYS, but no nonstop service.

Which airlines fly from MFR to TYS?

Airlines represented in the current schedule are United Airlines (UA).

Which aircraft fly from MFR to TYS?

Aircraft listed in the current schedule include Embraer 175 (long wing) (E7W).