MAD and LOS are approximately 2,382 miles apart by great-circle distance.
Yes. Roame's current schedule feed shows nonstop service from MAD to LOS.
Airlines represented in the current schedule are Smartwings (QS) and Sun Express Germany (XG).
Aircraft listed in the current schedule include Airbus A340-300 (343) and Boeing 737-800 Winglets (73H).