Holiday Inn Amarillo West Medical Center

Welcome to our beautiful hotel in Amarillo, Texas! Nestled in the heart of the Texas Panhandle, our hotel puts you near Amarillo’s best attractions. The iconic Cadillac Ranch is just 10 minutes away on historic Route 66. The second-largest canyon in the United States—Palo Duro Canyon—is an easy 30-minute drive from our Amarillo hotel. And with a location right off I-40, our hotel is a convenient stop whether you’re passing through or staying awhile. When you're not exploring Amarillo, take advantage of our exceptional meeting space, perfect for conferences, corporate events, and social gatherings. Our versatile venues feature state-of-the-art technology, customizable layouts, and seamless service to ensure a successful event. After a productive day, dine at Flame Grill Restaurant and Bar for breakfast and dinner, stay active in our fitness center, or unwind in our spacious pool and jacuzzi. In your comfortable room, you’ll find an ergonomic workspace, a lounge chair, plush beds, and a flat-screen TV. We look forward to welcoming you to an oasis of rest and relaxation at our hotel in Amarillo!